Uncovering the Latest Trends in Oncology Clinical Trials for World Cancer Day

World Cancer Day is observed on February 4th every year. It is a global initiative to raise awareness about cancer, its causes, and ways to prevent and treat it. In line with the theme for this year “Close the Care Gap”, Navitas Life Sciences supports efficient cancer clinical trials to help bring life saving drugs to the market sooner.

Oncology Clinical Trials at Navitas Life Sciences

With cancer being second most likely cause of death (after cardiac-related diseases), the focus on developing new oncotherapeutics is immense. However, the traditional drug development pathways in cancer therapeutics have been too slow and have the lowest clinical trial success rate of all major diseases. The answer to this critical problem lies in efficient innovative trials wherein multiple scientific hypothesis can be tested under the ambit of one protocol, called “master protocols”. They not only increase the success rate but also recognize failure faster and at lower cost, to allow the resources and efforts to be directed in an optimized way.

Navitas Life Sciences has supported 600+ clinical trials across 20+ therapeutic areas, including oncology.

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Recently, Dr. Atul Gupta, Vice President-Medical & Scientific Affairs, Navitas Life Sciences, and Venkatesan Balu, Associate Director – Global Data Sciences, Navitas Life Sciences, hosted a webinar titled “Innovation and Optimization in Early Phase Oncology Studies: Opportunity for speed, success and savings” to guide forward about managing oncology clinical trials with innovation and optimization.

Here are 5 Gains from the webinar on “Innovation and Optimization in Early Phase Oncology Studies: Opportunity for speed, success and savings”

1) Access to experts: Our exclusive webinars provide access to leading experts in the field of clinical trials, offering participants the opportunity to ask questions and gain insights from experienced professionals.

Dr. Atul Gupta

Vice President-Medical & Scientific Affairs
Navitas Life Sciences

More about our experts who conducted this webinar:

Dr. Atul Gupta is a physician and has worked as the Global Medical Lead in more than 50 studies across diverse therapeutic areas (Oncology, neurology, infectious diseases, cardiology, vaccines, biosimilars, GI, Haematology etc), across all the phases (I-IV) for drugs, devices and combination products.

His session during the webinar included insights about innovation oncology clinical trial designs.

Venkatesan Balu

Associate Director – Global Data Sciences
Navitas Life Sciences

Venkatesan Balu has vast experience in the domain of Biostatistics with an exposure to Phase I to Phase IV Clinical Trials in various therapeutic areas, and BABE or PK studies. He has the invaluable expertise in providing inputs on study design, sample size, SAP, outlier evaluation, and more. He is a Technical leader in drug development strategy, adaptive design, portfolio optimization, and decision-making in clinical trials.

His session during the webinar included key insights about statistical designs in early phase oncology study.

2) Latest Information: The webinar provided some of the latest information and developments in managing oncology clinical trials.

Our webinar discusses some of the issues that plague efficient management of clinical trials and ways to overcome them

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3) Convenient learning: Our webinars are easily accessible from anywhere, making it easy to gain key insights.

Statistical designs in Early Phase Oncology

Nonparametric and Algorithm-Based Designs to Calculate MTD

Traditional design

  • Design without dose de-escalation
  • Design with dose de-escalation

Accelerated Titration Design

  • Rapid acceleration phase
  • Intra-patient dose escalation phase
  • Assessment of dose-toxicity relationship

Bayesian Algorithm-Based Designs

  • Toxicity posterior intervals (TPI)
  • Beta-binomial model (BBM)
  • Isotonic Designs

4) Cost and Time effective strategies: Navitas Life Sciences allocates attention, effort and resources to instill cost and time effectiveness into its clinical trial strategies. The contribution of such strategies aid in achieving goals such as reducing cost across value chains, offering competence and enhanced practices to support adherence to budgets and timelines.

The webinar discusses some sallient aspects of efficiencies that are possible through the use of innovative strategies.

5) Easy access to resources: Navitas Life Sciences’ webinars include on-demand slides, brochures and case study resources that can be accessed and downloaded after the event, providing participants with valuable information to reference in the future.

Navitas Life Sciences’ oncology webinar is an experience focused on the future of oncology clinical trials. The insights shared during the webinar include some of the challenges faced when trying to bring oncology drugs to markets worldwide. The webinar was developed using learning formats that ensured every attendee benefits from the learning.

On-Demand Webinar: Innovation and Optimization in Early Phase Oncology Studies: Opportunity for speed, success and savings

Listen to our On-demand webinar as our subject matter experts explores key themes regarding

  • How applying innovative designs in early phase oncology trials can accelerate timelines and reduce costs
  • How to focus development on the most promising agents at the right doses in the right indications for the right patients.
  • Simple strategies on Dose Escalation: A legacy of statistical innovation
  • Expert insights on Novel endpoints to sail through dose expansion and proof of concept

To know more about our services and solutions, reach out to us at This email address is being protected from spambots. You need JavaScript enabled to view it.

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